Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HEXA | P06865 | 4/20 | 0.42 |
| ▸ | HEXB | P07686 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716942 | 0.88 | PRMT1 (0.46) | BCL2MCL1PRMT1POLBLMNA | |
| SCHEMBL11712854 | 0.85 | PRMT1 (0.65) | MCL1PRMT1POLBLMNAKDM4E | |
| SCHEMBL11718179 | 0.80 | ALDH1A1 (0.51) | BCL2MCL1PRMT1POLBLMNA | |
| SCHEMBL11712263 | 0.79 | PRMT1 (0.49) | PRMT1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL11719752 | 0.79 | PRMT1 (0.44) | BCL2MCL1PRMT1POLBLMNA | |
| SCHEMBL11714120 | 0.79 | BCL2 (0.48) | BCL2MCL1PRMT1POLBLMNA | |
| SCHEMBL11714622 | 0.78 | PRMT1 (0.46) | BCL2MCL1PRMT1POLBLMNA | |
| SCHEMBL11715700 | 0.78 | PRMT1 (0.48) | PRMT1POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL11716443 | 0.77 | KMT2A (0.46) | BCL2MCL1PRMT1POLBLMNA | |
| SCHEMBL11718368 | 0.77 | MCL1 (0.54) | BCL2MCL1PRMT1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |