Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718442 | 1.00 | MEN1 (0.46) | MEN1KMT2APOLBALDH1A1HCRTR2 | |
| SCHEMBL13101308 | 0.86 | ABCB1 (0.46) | MEN1KMT2APOLBALDH1A1FFAR2 | |
| SCHEMBL13091659 | 0.86 | ABCB1 (0.46) | MEN1KMT2APOLBALDH1A1FFAR2 | |
| SCHEMBL3075753 | 0.86 | ABCB1 (0.46) | MEN1KMT2APOLBALDH1A1FFAR2 | |
| SCHEMBL3075751 | 0.86 | ABCB1 (0.46) | MEN1KMT2APOLBALDH1A1FFAR2 | |
| SCHEMBL13091625 | 0.85 | POLB (0.48) | MEN1KMT2APOLBALDH1A1FFAR2 | |
| SCHEMBL4753899 | 0.84 | HSD17B10 (0.45) | MEN1KMT2APOLBALDH1A1FFAR2 | |
| SCHEMBL11716085 | 0.83 | FFAR2 (0.40) | MEN1KMT2APOLBALDH1A1HCRTR2 | |
| SCHEMBL11716080 | 0.83 | FFAR2 (0.40) | MEN1KMT2APOLBALDH1A1HCRTR2 | |
| SCHEMBL11714017 | 0.82 | AKT1 (0.43) | MEN1KMT2APOLBALDH1A1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009172-A | 2,3,3A,6,7,7A-Hexahydro-thieno[3,2-b]pyridin-(4H)5-ones | HOFFMANN-LA ROCHE INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3957794-A | 3-Amino-2,3,3a,6,7,7a-hexahydro-thieno[3,2-b]pyridin-(4H)5-one | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |