Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077776 | 0.84 | HPGD (0.47) | HPGDKMT2AMEN1CNR1POLB | |
| SCHEMBL14482311 | 0.79 | HPGD (0.49) | NPC1HPGDKMT2AMEN1POLB | |
| SCHEMBL11715829 | 0.79 | HPGD (0.49) | NPC1HPGDKMT2AMEN1POLB | |
| SCHEMBL14482310 | 0.79 | HPGD (0.49) | NPC1HPGDKMT2AMEN1POLB | |
| SCHEMBL11712593 | 0.77 | CHRNA7 (0.46) | NPC1HPGDKMT2AMEN1POLB | |
| SCHEMBL6906944 | 0.70 | TSHR (0.51) | NPC1HPGDKMT2AMEN1POLB | |
| SCHEMBL12409415 | 0.69 | ALDH1A1 (0.48) | NPC1GLAHPGDKMT2AMEN1 | |
| SCHEMBL11713719 | 0.69 | KMT2A (0.54) | NPC1HPGDKMT2AMEN1POLB | |
| SCHEMBL12409439 | 0.69 | ALDH1A1 (0.47) | NPC1GLAHPGDKMT2AMEN1 | |
| SCHEMBL136736 | 0.69 | ALDH1A1 (0.42) | HPGDKMT2AMEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029646-A | Benzyl N,N-hexamethylenethiolcarbamate compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |
| US-4005071-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |