Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | GRM6 | O15303 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683884 | 0.80 | ALDH1A1 (0.45) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL470719 | 0.79 | ALDH1A1 (0.43) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL1901754 | 0.78 | PSEN1 (0.45) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL8311723 | 0.77 | EPHX2 (0.44) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL66816 | 0.76 | ATM (0.39) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL9871837 | 0.76 | ATM (0.39) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL9973081 | 0.74 | CYP2C9 (0.50) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL6702128 | 0.74 | BTK (0.46) | CYP2C9 | |
| SCHEMBL1896872 | 0.73 | SMN1; SMN2 (0.48) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 | |
| SCHEMBL24556900 | 0.73 | PSEN1 (0.47) | CYP2C9CYP2C19ATMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064258-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |