SCHEMBL117198

SCHEMBL117198

NC(=O)c1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
ATM Q13315 1/20 1.00
GPR84 Q9NQS5 1/20 0.71
PBRM1 Q86U86 1/20 0.67
PIM1 P11309 2/20 0.61
PIM3 Q86V86 1/20 0.61
NR4A2 P43354 2/20 0.61
MAPK1 P28482 1/20 0.61
CREBBP Q92793 1/20 0.61
KMT2A Q03164 3/20 0.57
ADAM17 P78536 1/20 0.57
CTNNB1 P35222 2/20 0.56
WNT3A P56704 2/20 0.56
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
MEN1 O00255 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
LMNA P02545 1/20 0.53
HTR3E A5X5Y0 1/20 0.53
HTR3B O95264 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27785298 1.00 ALDH1A1 (1.00) ALDH1A1ATMGPR84PBRM1PIM1
SCHEMBL29544426 1.00 ALDH1A1 (1.00) ALDH1A1ATMGPR84PBRM1PIM1
Hydrochloric Acid SCHEMBL28283733 0.98 ALDH1A1 (0.96) ALDH1A1ATMGPR84PBRM1PIM1
Hydrochloric Acid SCHEMBL28283888 0.98 ALDH1A1 (0.96) ALDH1A1ATMGPR84PBRM1PIM1
Hydrochloric Acid SCHEMBL7400951 0.98 ALDH1A1 (0.96) ALDH1A1ATMGPR84PBRM1PIM1
Hydrochloric Acid SCHEMBL29715885 0.98 ALDH1A1 (0.96) ALDH1A1ATMGPR84PBRM1PIM1
SCHEMBL27721352 0.96 ALDH1A1 (0.93) ALDH1A1ATMGPR84PBRM1PIM1
Acetic Acid SCHEMBL30661849 0.93 ALDH1A1 (0.86) ALDH1A1ATMGPR84PBRM1PIM1
Trifluoroacetic Acid SCHEMBL28105351 0.88 ALDH1A1 (0.78) ALDH1A1ATMGPR84PBRM1PIM1
SCHEMBL29450818 0.87 ALDH1A1 (0.77) ALDH1A1ATMGPR84PBRM1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2306 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056281-A Application of indoleamide compound as linker for mediating interaction of ubiquitin ligase and effector protein 中国农业大学 2026-05-19 CN claimed
US-12465588-B2 Indole carboxamide derivative and pharmaceutical composition containing same KUKJE PHARMA CO., LTD. (KR) 2025-11-11 US claimed
CN-114729004-B Heterocyclic compounds 日商泛美克斯股份有限公司 2025-06-03 CN claimed
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN claimed
US-20250082652-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES UNIVERSITÄT ZU KÖLN (DE) 2025-03-13 US claimed
CN-114302874-B Indole carboxamide derivatives and pharmaceutical compositions containing the same 国际药品株式会社 2025-02-25 CN claimed
US-20250032629-A1 NOVEL NUCLEOLIN-BINDING PEPTIDE AND USE THEREOF ANYGEN CO., LTD. (KR) 2025-01-30 US claimed
CN-119306650-A Preparation method of indole carboxamide compound 西安睿舒维生物医药科技有限公司 2025-01-14 CN claimed
CN-118638038-B N-axis chiral indole amide compound and synthesis method thereof 常州大学 2024-12-03 CN claimed
EP-4460301-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES Universität zu Köln (DE) 2024-11-13 EP claimed
EP-0347229-A1 Indole derivatives GLAXO GROUP LIMITED (GB) 1989-12-20 EP claimed
US-4791109-A Novel indole carboxamides ROUSSEL UCLAF (FR) 1988-12-13 US claimed
EP-0150505-B1 3-INDOLECARBOXAMIDE COMPOUNDS Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-04-01 EP claimed
EP-0144986-B1 INDOLE-3-CARBOXAMIDE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-03-04 EP claimed
US-4616009-A PSYCHOLOGICAL DISORDERS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1986-10-07 US claimed
US-4581355-A HYPOTENSIVE AGENTS, LIPOXYGENASE INHIBITORS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1986-04-08 US claimed
US-4576940-A ANHISTAMINE YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1986-03-18 US claimed
EP-0150505-A2 3-Indolecarboxamide compounds Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-08-07 EP claimed
EP-0144986-A2 Indole-3-carboxamide derivatives Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-19 EP claimed
EP-0137163-A2 3-Indolecarboxamide derivatives Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-04-17 EP claimed