Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715706 | 0.86 | MAPT (0.56) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL14919144 | 0.84 | NOTUM (0.61) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL13601328 | 0.83 | KDM4E (0.63) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL18109146 | 0.82 | LMNA (0.67) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL13597692 | 0.81 | KDM4E (0.55) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL11710804 | 0.80 | KDM4E (0.60) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL12615985 | 0.80 | NOTUM (0.78) | KCNJ1NOTUMALDH1A1MAPTF2 | |
| Dimethyl Sulfone SCHEMBL20720495 | 0.80 | NOTUM (0.78) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL11711923 | 0.78 | KDM4E (0.55) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 | |
| SCHEMBL11744377 | 0.78 | KDM4E (0.55) | KDM4EMAPK1KCNJ1NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036849-A | ANTIMICROBIAL | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | claimed |
| US-4036849-A | ANTIMICROBIAL | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | disclosed |