Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719448 | 0.81 | KMT2A (0.70) | MAPTKMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3605374 | 0.77 | CYP2D6 (0.48) | TSHRCCR2ALDH1A1MAPK1HIF1A | |
| SCHEMBL321353 | 0.76 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL321354 | 0.76 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL5003118 | 0.76 | HIF1A (0.69) | KMT2ATSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4611641 | 0.76 | HIF1A (0.69) | KMT2ATSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7825778 | 0.75 | CCR3 (0.75) | — | |
| SCHEMBL7821639 | 0.74 | CCR3 (0.65) | — | |
| SCHEMBL321262 | 0.74 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL321263 | 0.74 | ROCK2 (0.68) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065291-A | Herbicidal 1-(2-hydroxymethylpyrrolidinyl) carboxanilides | CHEVRON RESEARCH COMPANY (US) | 1977-12-27 | — | — | US | disclosed |