Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715778 | 0.89 | LMNA (0.51) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11736483 | 0.83 | LMNA (0.60) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11739087 | 0.83 | CYP1A2 (0.53) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11235123 | 0.82 | LMNA (0.62) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| Bromide SCHEMBL11739763 | 0.82 | LMNA (0.58) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11740959 | 0.81 | LMNA (0.43) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11742793 | 0.81 | LMNA (0.56) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL21550 | 0.79 | LMNA (0.59) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11786309 | 0.79 | CYP1A2 (0.49) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11740713 | 0.78 | LMNA (0.57) | LMNAKMT2AMEN1CYP1A2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | claimed |
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |
| US-4036631-A | Pyrazolone derivatives and their use as herbicides | SANKYO COMPANY LIMITED (JA) | 1977-07-19 | — | — | US | disclosed |