Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155702 | 0.84 | CTSB (0.51) | CTSBCTSHALDH1A1POLBTSHR | |
| SCHEMBL6836387 | 0.79 | TSHR (0.40) | CTSBCTSHALDH1A1KCNMA1POLB | |
| SCHEMBL30639971 | 0.79 | MAPT (0.50) | KCNMA1POLBTSHRPARP1MAPT | |
| SCHEMBL669235 | 0.79 | MAPT (0.50) | KCNMA1POLBTSHRPARP1MAPT | |
| SCHEMBL14358005 | 0.79 | CTSB (0.47) | CTSBCTSHALDH1A1POLBTSHR | |
| SCHEMBL11638553 | 0.78 | MAPK1 (0.49) | CTSBCTSHALDH1A1POLBTSHR | |
| SCHEMBL11620115 | 0.76 | PARP1 (0.46) | ALDH1A1POLBPARP1MAPTSMN1; SMN2 | |
| SCHEMBL801581 | 0.76 | CTSB (0.62) | CTSBCTSHALDH1A1POLBTSHR | |
| SCHEMBL782344 | 0.74 | MAPT (0.54) | ALDH1A1POLBPARP1CYP3A4MAPT | |
| SCHEMBL801582 | 0.74 | CTSB (0.51) | CTSBCTSHALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |