Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719570 | 0.85 | — | — | |
| SCHEMBL7079823 | 0.84 | — | — | |
| SCHEMBL9458718 | 0.76 | — | — | |
| SCHEMBL11718275 | 0.74 | — | — | |
| SCHEMBL11722580 | 0.70 | EPHX1 (0.30) | — | |
| SCHEMBL649656 | 0.69 | CA2 (0.44) | MAPTGAAALDH1A1KDM4E | |
| SCHEMBL418942 | 0.69 | CA2 (0.44) | MAPTGAAALDH1A1KDM4E | |
| SCHEMBL368709 | 0.69 | CA2 (0.44) | MAPTGAAALDH1A1KDM4E | |
| SCHEMBL11721771 | 0.69 | CA2 (0.33) | ALDH1A1 | |
| SCHEMBL11722842 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060532-A | Halogenated dioxolane tranquilizers | ICI UNITED STATES INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3996376-A | Halogenated dioxolane tranquilizers | ICI UNITED STATES INC. (US) | 1976-12-07 | — | — | US | disclosed |