Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720747 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL8430294 | 0.93 | MEN1 (0.47) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL8430296 | 0.93 | MEN1 (0.47) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL14032325 | 0.87 | MEN1 (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL25669486 | 0.87 | MEN1 (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8655219 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPT | |
| SCHEMBL27569641 | 0.85 | HDAC3 (0.50) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13906640 | 0.85 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPTGLO1 | |
| SCHEMBL8657420 | 0.85 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPTGLO1 | |
| SCHEMBL13906641 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038414-A | ANTIARRHYTHMIA AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4014920-A | N-cinnamylcarbamic acid esters | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |