Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 8/20 | 0.66 |
| ▸ | CCR1 | P32246 | 9/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Difenoxin SCHEMBL123801 | 0.91 | KCNA3 (0.78) | KCNA3CCR1OPRM1RAB9ANPSR1 | |
| Difenoxin SCHEMBL11604884 | 0.90 | KCNA3 (0.76) | KCNA3CCR1OPRM1RAB9ANPSR1 | |
| Difenoxin SCHEMBL149008 | 0.90 | KCNA3 (0.76) | KCNA3CCR1OPRM1RAB9ANPSR1 | |
| SCHEMBL11732757 | 0.87 | KCNA3 (0.81) | KCNA3CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL11606215 | 0.85 | KCNA3 (0.67) | KCNA3CCR1OPRM1RAB9ANPSR1 | |
| SCHEMBL9106795 | 0.84 | CCR1 (0.70) | KCNA3CCR1OPRM1CCR3 | |
| SCHEMBL10064332 | 0.82 | KCNA3 (0.78) | KCNA3CCR1OPRM1RAB9ANPSR1 | |
| Diphenoxylate SCHEMBL8160138 | 0.81 | OPRM1 (0.94) | KCNA3OPRM1 | |
| Hydrochloric Acid SCHEMBL11604880 | 0.81 | KCNA3 (0.73) | KCNA3CCR1OPRM1RAB9ANPSR1 | |
| SCHEMBL11604250 | 0.81 | KCNA3 (0.84) | KCNA3CCR1OPRM1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017491-A | 1,1-Diaryl-1H-tetrazole amines | G. D. SEARLE & CO. (US) | 1977-04-12 | — | — | US | disclosed |
| US-4003904-A | Anti-diarrheal oxadiazoles | G. D. SEARLE & CO. (US) | 1977-01-18 | — | — | US | disclosed |