Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22165366 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HTTMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL28421614 | 0.79 | ERN1 (0.46) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL29953130 | 0.79 | ERN1 (0.54) | ERN1ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL15335030 | 0.79 | IDO1 (0.47) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL30517071 | 0.79 | ERN1 (0.46) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL25257439 | 0.79 | ERN1 (0.46) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL12328353 | 0.79 | ERN1 (0.46) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL30203960 | 0.79 | ERN1 (0.46) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL14140286 | 0.78 | ERN1 (0.51) | ERN1ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL28209177 | 0.78 | ERN1 (0.42) | ERN1ALDH1A1HTTMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | claimed |
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |