SCHEMBL11722844

SCHEMBL11722844

CC(C)(CC(C)(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.72
ESR1 P03372 14/20 0.57
ESR2 Q92731 12/20 0.57
CYP3A4 P08684 4/20 0.52
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52
AR P10275 1/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11352348 0.92 SHBG (0.62) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL3967698 0.88 SHBG (0.60) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL11726495 0.87 SHBG (0.56) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL11721914 0.86 ESR1 (0.56) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL18622729 0.84 SHBG (0.75) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL31282065 0.84 SHBG (1.00) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL11538806 0.84 SHBG (0.68) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL10141 0.84 SHBG (1.00) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL22773183 0.82 SHBG (0.95) SHBGESR1ESR2CYP3A4LMNA
Hydrogen Sulfide SCHEMBL10824257 0.82 SHBG (0.95) SHBGESR1ESR2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059638-A Trisphenol process BAYER AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed