Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 10/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723511 | 0.92 | HRH1 (0.47) | GLAEGFRERBB2HRH1LMNA | |
| SCHEMBL11724259 | 0.86 | EGFR (0.41) | GLAEGFRERBB2BRD4HRH1 | |
| SCHEMBL11725390 | 0.85 | ALDH1A1 (0.52) | BRD4KDRLMNAPKMALDH1A1 | |
| SCHEMBL11727356 | 0.83 | ALDH1A1 (0.45) | BRD4KDRLMNAPKMALDH1A1 | |
| SCHEMBL11723912 | 0.82 | HRH1 (0.48) | GLAEGFRERBB2HRH1LMNA | |
| SCHEMBL11725307 | 0.81 | POLB (0.46) | KDRPKMALDH1A1MAPTCXCR3 | |
| SCHEMBL11720483 | 0.81 | CA12 (0.43) | EGFRERBB2KDRLMNAPKM | |
| Hydrochloric Acid SCHEMBL11724250 | 0.80 | POLB (0.45) | KDRPKMALDH1A1MAPTHPGD | |
| SCHEMBL11724229 | 0.79 | ALDH1A1 (0.49) | LMNAPKMALDH1A1KDM4E | |
| SCHEMBL11725333 | 0.79 | ALDH1A1 (0.59) | GLALMNAPKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |