Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728283 | 0.87 | ALDH1A1 (0.46) | GAAKMT2AMAPTHPGDMEN1 | |
| SCHEMBL11724515 | 0.84 | KMT2A (0.50) | GAAATMKMT2AMAPTHPGD | |
| SCHEMBL11720739 | 0.77 | ALDH1A1 (0.39) | GAAATMKMT2AMAPTHPGD | |
| SCHEMBL2570620 | 0.76 | KMT2A (0.55) | KMT2AMAPTHTTNPC1CYP3A4 | |
| SCHEMBL12678010 | 0.76 | HCAR2 (0.55) | ATMKMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL27884533 | 0.76 | ALDH1A1 (0.57) | ATMKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL287220 | 0.76 | ALDH1A1 (0.56) | GAAKMT2AMAPTHPGDMEN1 | |
| SCHEMBL29960870 | 0.75 | NPC1 (0.61) | GAAKMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL29083934 | 0.75 | NPC1 (0.61) | GAAKMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL31226521 | 0.75 | GAA (0.50) | GAAATMKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | claimed |
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |