Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477506 | 0.89 | LMNA (0.63) | RAB9ASMN1; SMN2MAPTMAOBBCHE | |
| SCHEMBL10543846 | 0.87 | MAOB (0.61) | NPC1RAB9ASMN1; SMN2MAPTMAOB | |
| SCHEMBL3239740 | 0.87 | LMNA (0.66) | RAB9ASMN1; SMN2MAPTMAOBBCHE | |
| SCHEMBL23882779 | 0.85 | APP (0.51) | FFAR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL23882781 | 0.85 | APP (0.51) | FFAR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL477466 | 0.85 | ACP3 (0.61) | NPC1RAB9AMAPTKMT2A | |
| SCHEMBL477389 | 0.85 | ACP3 (0.61) | NPC1RAB9AMAPTKMT2A | |
| SCHEMBL477621 | 0.85 | ACP3 (0.61) | NPC1RAB9AMAPTKMT2A | |
| SCHEMBL553770 | 0.83 | APP (0.69) | FFAR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL13140291 | 0.82 | FFAR1 (0.81) | FFAR1NPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061629-A | 6-Amino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4029669-A | 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-3965093-A | 6-Arylthio penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |