Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727202 | 0.94 | HRH3 (0.54) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL12338663 | 0.89 | HRH3 (0.33) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL10645198 | 0.86 | HRH3 (0.48) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL24162861 | 0.82 | PAOX (0.43) | SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14331397 | 0.80 | KEAP1 (0.44) | SMN1; SMN2ALOX15 | |
| SCHEMBL6946106 | 0.80 | SMN1; SMN2 (0.48) | CYP1A2MAPK1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28752459 | 0.80 | CXCR4 (0.46) | HRH3SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL3997403 | 0.79 | HRH3 (0.50) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL31528856 | 0.77 | HRH3 (0.46) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL23465166 | 0.76 | HRH3 (0.46) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045483-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4009163-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3988370-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1976-10-26 | — | — | US | disclosed |