Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720104 | 0.82 | ALDH1A1 (0.38) | CXCR3ALDH1A1SMN1; SMN2PKMRAB9A | |
| SCHEMBL11724279 | 0.78 | BRD4 (0.41) | CXCR3IRAK4ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL11727141 | 0.76 | KDM4E (0.41) | IRAK4ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL11725537 | 0.73 | IRAK4 (0.38) | CXCR3IRAK4ALDH1A1PKMRAB9A | |
| SCHEMBL11725524 | 0.73 | ALDH1A1 (0.47) | CXCR3IRAK4ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL11725530 | 0.72 | ALDH1A1 (0.39) | IRAK4ALDH1A1PKMRAB9ARXFP1 | |
| SCHEMBL11725390 | 0.70 | ALDH1A1 (0.52) | CXCR3IRAK4ALDH1A1PKMRAB9A | |
| SCHEMBL27154650 | 0.67 | KDM4E (0.61) | ALDH1A1SMN1; SMN2RAB9AGAATSHR | |
| SCHEMBL3465555 | 0.67 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9AGAAMEN1 | |
| SCHEMBL10402053 | 0.66 | MAPT (0.43) | ALDH1A1SMN1; SMN2RAB9AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053472-A | MICROBIOCIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |