Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723706 | 0.91 | CYP2C19 (0.36) | CYP2C19RXFP1LMNAALDH1A1THRB | |
| SCHEMBL11843203 | 0.90 | CYP2C19 (0.35) | CYP2C19RXFP1LMNAALDH1A1THRB | |
| SCHEMBL11732256 | 0.82 | RXFP1 (0.34) | CYP2C19RXFP1 | |
| SCHEMBL11777882 | 0.82 | MAPT (0.40) | CYP2C19LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11842731 | 0.82 | SMN1; SMN2 (0.40) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11850406 | 0.82 | CYP2C19 (0.39) | CYP2C19ALDH1A1 | |
| SCHEMBL11740246 | 0.80 | SMN1; SMN2 (0.32) | CYP2C19SMN1; SMN2 | |
| SCHEMBL11728528 | 0.78 | LMNA (0.39) | CYP2C19RXFP1LMNAALDH1A1THRB | |
| SCHEMBL11725247 | 0.78 | LMNA (0.39) | CYP2C19RXFP1LMNAALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL11725208 | 0.77 | LMNA (0.38) | CYP2C19RXFP1LMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-3991200-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1976-11-09 | — | — | US | disclosed |