Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725999 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11722357 | 0.88 | PTGFR (0.52) | KDM4EALDH1A1PTGER4PTGER3PTGFR | |
| SCHEMBL11722362 | 0.88 | PTGFR (0.52) | KDM4EALDH1A1PTGER4PTGER3PTGFR | |
| SCHEMBL11722473 | 0.87 | PPARG (0.52) | KDM4EALDH1A1PGRADORA3SLC6A2 | |
| SCHEMBL11722471 | 0.87 | PPARG (0.52) | KDM4EALDH1A1PGRADORA3SLC6A2 | |
| SCHEMBL11718528 | 0.86 | PPARG (0.53) | KDM4EALDH1A1TDP1OXER1PGR | |
| SCHEMBL11718533 | 0.86 | PPARG (0.53) | KDM4EALDH1A1TDP1OXER1PGR | |
| SCHEMBL11599487 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599493 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599490 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054741-A | Derivatives of prostanoic acid | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-10-18 | — | — | US | disclosed |