Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599490 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599487 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11105296 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599917 | 0.86 | POLB (0.44) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599914 | 0.86 | POLB (0.44) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599921 | 0.86 | POLB (0.44) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11725999 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11726005 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL18965693 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11598003 | 0.73 | PTGFR (0.42) | ALDH1A1PTGER4PTGER3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092427-A | ANTICOAGULANTS, OXYTOCICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4048329-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048328-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |