Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726568 | 0.90 | CA12 (0.52) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL11726826 | 0.84 | MEN1 (0.55) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL10885870 | 0.83 | RECQL (0.59) | CA12MEN1GFERKMT2AESR1 | |
| SCHEMBL12556877 | 0.83 | TDP1 (0.56) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL11623896 | 0.82 | ALDH1A1 (0.55) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL11723655 | 0.82 | MEN1 (0.53) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL11723903 | 0.81 | ESR1 (0.50) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL11721600 | 0.80 | MEN1 (0.52) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL11724665 | 0.80 | KMT2A (0.52) | CA12MEN1GFERKMT2AESR1 | |
| SCHEMBL11723618 | 0.79 | MEN1 (0.51) | CA12CA9CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |