Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.61 |
| ▸ | PTGFR | P43088 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.61 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.61 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.61 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717844 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11727049 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11717851 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11720178 | 0.99 | TBXA2R (0.62) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11729894 | 0.95 | ALDH1A1 (0.69) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11719232 | 0.95 | ALDH1A1 (0.69) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11718603 | 0.95 | ALDH1A1 (0.69) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11718599 | 0.95 | ALDH1A1 (0.69) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11719228 | 0.95 | ALDH1A1 (0.69) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 | |
| SCHEMBL11721428 | 0.94 | TBXA2R (0.65) | ALDH1A1TBXA2RPTGFRLMNAPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054741-A | Derivatives of prostanoic acid | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-10-18 | — | — | US | disclosed |