Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727928 | 1.00 | LMNA (0.32) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11725440 | 0.80 | LMNA (0.36) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11725235 | 0.78 | LMNA (0.39) | LMNAALDH1A1THRBTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11725202 | 0.77 | LMNA (0.38) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11728516 | 0.76 | LMNA (0.39) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11723698 | 0.75 | CYP2C19 (0.36) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11725469 | 0.74 | LMNA (0.35) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11732198 | 0.74 | LMNA (0.33) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11727943 | 0.73 | LMNA (0.32) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL11721210 | 0.73 | LMNA (0.41) | LMNAALDH1A1THRBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-3991200-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1976-11-09 | — | — | US | disclosed |