Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731428 | 0.95 | FFAR4 (0.47) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11728631 | 0.89 | FFAR4 (0.44) | FFAR4FFAR1EPHX2 | |
| SCHEMBL11730813 | 0.85 | FFAR4 (0.40) | FFAR4FFAR1EPHX2 | |
| SCHEMBL11728529 | 0.85 | FFAR4 (0.36) | FFAR4FFAR1EPHX2 | |
| SCHEMBL11602008 | 0.84 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL11601264 | 0.84 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL4964157 | 0.84 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL11602010 | 0.84 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL9629085 | 0.80 | FFAR4 (0.70) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11729893 | 0.79 | CA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |