Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264219 | 0.86 | HRH2 (0.50) | MAOBKMT2AHSD17B3 | |
| SCHEMBL28936624 | 0.86 | HRH2 (0.50) | MAOBKMT2AHSD17B3 | |
| SCHEMBL7814459 | 0.85 | MAOB (0.54) | MAOBNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8392453 | 0.84 | MAOB (0.57) | MAOBNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL11219615 | 0.83 | MAOB (0.53) | MAOBNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL14757597 | 0.80 | MAOB (0.57) | MAOBNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL28703131 | 0.80 | NPC1 (0.48) | MAOBNPC1RAB9AKMT2AHPGD | |
| SCHEMBL28719788 | 0.79 | MAOB (0.53) | MAOBNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL28713425 | 0.79 | NPC1 (0.61) | MAOBNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL6834190 | 0.78 | MAOB (0.56) | MAOBNPC1RAB9ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002643-A | REARRANGING WITH A STRONG, ANHYDROUS, NON-OXIDIZING ACID | MCNEIL LABORATORIES, INC. (US) | 1977-01-11 | — | — | US | disclosed |