Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799349 | 0.84 | NR4A2 (0.61) | MAOBNR4A2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7814459 | 0.83 | MAOB (0.54) | MAOBRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL11728742 | 0.83 | MAOB (0.54) | MAOBRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL28713425 | 0.81 | NPC1 (0.61) | MAOBRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL14757597 | 0.79 | MAOB (0.57) | MAOBRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL8392453 | 0.79 | MAOB (0.57) | MAOBRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL28719788 | 0.77 | MAOB (0.53) | MAOBRAB9ANPC1SMN1; SMN2PKM | |
| SCHEMBL9264219 | 0.77 | HRH2 (0.50) | MAOBKMT2AALDH1A1FFAR1 | |
| SCHEMBL28936624 | 0.77 | HRH2 (0.50) | MAOBKMT2AALDH1A1FFAR1 | |
| SCHEMBL6834190 | 0.77 | MAOB (0.56) | MAOBRAB9ANPC1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342689-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342690-A | HHYPOTENSIVE AGE TS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342691-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4299769-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | disclosed |