Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726508 | 0.88 | PPARA (0.37) | THRATHRBPPARGPPARAPLA2G4B | |
| SCHEMBL11726045 | 0.83 | PTGER4 (0.42) | PLA2G4BTP53TSHRMLYCD | |
| SCHEMBL11732095 | 0.83 | PTGER4 (0.42) | PLA2G4BTP53TSHRMLYCD | |
| SCHEMBL11728550 | 0.83 | PTGER4 (0.42) | PLA2G4BTP53TSHRMLYCD | |
| SCHEMBL11737885 | 0.83 | PTGER4 (0.42) | PLA2G4BTP53TSHRMLYCD | |
| SCHEMBL11726784 | 0.83 | PTGER4 (0.42) | PLA2G4BTP53TSHRMLYCD | |
| SCHEMBL11734570 | 0.78 | PPARG (0.35) | THRATHRBPPARGPPARAPLA2G4B | |
| SCHEMBL11732180 | 0.78 | MGLL (0.39) | THRATHRBPLA2G4BTP53TSHR | |
| SCHEMBL11734581 | 0.78 | ESRRA (0.42) | THRATHRBPPARGPPARAESRRA | |
| SCHEMBL11735641 | 0.75 | FFAR1 (0.42) | THRATHRBESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008327-A | ANTIDIABETIC | SANDOZ, INC. (US) | 1977-02-15 | — | — | US | disclosed |