Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | EEF2K | O00418 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507659 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2PRNPRXFP1GAAKDM4E | |
| SCHEMBL529327 | 0.97 | SMN1; SMN2 (0.50) | SMN1; SMN2PRNPRXFP1GAAKDM4E | |
| SCHEMBL12507660 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2PRNPRXFP1GAAKDM4E | |
| SCHEMBL10144361 | 0.92 | PRNP (0.50) | SMN1; SMN2PRNPRXFP1GAAKDM4E | |
| SCHEMBL974373 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2PRNPRXFP1GAAKDM4E | |
| SCHEMBL31177107 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2PRNPRXFP1KDM4EALDH1A1 | |
| SCHEMBL7917387 | 0.79 | MEN1 (0.46) | SMN1; SMN2GAAKDM4EALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL31648022 | 0.79 | ALOX15 (0.39) | SMN1; SMN2PRNPRXFP1GAAKDM4E | |
| SCHEMBL6607763 | 0.79 | CYP3A4 (0.47) | SMN1; SMN2GAAALOX15POLBADRA2A | |
| SCHEMBL20682503 | 0.78 | PRNP (0.38) | SMN1; SMN2PRNPRXFP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831167-B1 | LIQUID PHASE PROCESS FOR THE SYNTHESIS OF ANNULATED PYRIDINES OVER ZEOLITE TYPE MOLECULAR SIEVE CATALYSTS | COUNCIL SCIENT IND RES (IN) | 2011-07-13 | — | — | EP | disclosed |
| US-7491828-B2 | Liquid phase process for the synthesis of annulated pyridines over molecular sieve catalysts | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-02-17 | — | — | US | disclosed |
| US-7491828-B2 | Liquid phase process for the synthesis of annulated pyridines over molecular sieve catalysts | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-02-17 | — | — | US | disclosed |
| US-4011226-A | ANTIULCER | JOHN WYETH & BROTHER LIMITED (EN) | 1977-03-08 | — | — | US | disclosed |