⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172704 | 0.93 | — | — | |
| SCHEMBL2939415 | 0.89 | THRB (0.35) | — | |
| SCHEMBL29205023 | 0.87 | THRB (0.40) | — | |
| SCHEMBL29116843 | 0.87 | THRB (0.40) | — | |
| SCHEMBL28517285 | 0.87 | HDAC3 (0.31) | — | |
| SCHEMBL2722135 | 0.87 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL6865444 | 0.87 | THRB (0.40) | — | |
| SCHEMBL6331154 | 0.87 | THRB (0.40) | — | |
| SCHEMBL28442863 | 0.87 | THRB (0.40) | — | |
| SCHEMBL28354425 | 0.87 | THRB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089436-B1 | POLYMERIZATION OF ACRYLIC POLYMERS IN REACTIVE DILUENTS | COATINGS FOREIGN IP CO LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-7888440-B2 | Solvent-free, high-solids, crosslinkable coatings for finishing automobile and truck exteriors; catalytically polymerizing acrylicesters in a liquid carrier and a diluent nonreactingat this point but subsequently reactive in coatings during cure (amide acetal-a 1-aza-4,6-dioxabicyclo[3.3.0]octane) | E. I. DU PONT DE NEMOURS & CO. (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080287622-A1 | Polymerization of acrylic polymers in reactive diluents | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2008-11-20 | — | — | US | disclosed |
| US-7288607-B2 | High solids primer composition based on epoxy ring opening curing reaction | E. I. DU PONT DE NEMOURS & CO. (US) | 2007-10-30 | — | — | US | disclosed |
| EP-1799760-A1 | HIGH SOLIDS PRIMER COMPOSITIONS BASED ON A CYCLOALIPHATIC EPOXY RESIN AND AN ALKOXY- SILANE AND / OR ALKOXY-SILICATE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006042299-A1 | HIGH SOLIDS PRIMER COMPOSITIONS BASED ON A CYCLOALIPHATIC EPOXY RESIN AND AN ALKOXY- SILANE AND / OR ALKOXY-SILICATE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060079637-A1 | High solids primer composition based on epoxy ring opening curing reaction | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-04-13 | — | — | US | disclosed |