Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810341 | 0.81 | MAPT (0.47) | MAPTPOLBTP53RXFP1RAB9A | |
| SCHEMBL11724471 | 0.80 | MAPT (0.63) | MAPTPOLBTP53RXFP1NPC1 | |
| SCHEMBL11725391 | 0.79 | CASP3 (0.55) | MAPTPOLBTP53RXFP1NPC1 | |
| SCHEMBL6354100 | 0.77 | MAPT (0.67) | MAPTPOLBTP53NPC1RAB9A | |
| SCHEMBL11799107 | 0.76 | MAPT (0.59) | MAPTPOLBTP53RXFP1NPC1 | |
| SCHEMBL13401396 | 0.75 | MAPT (0.64) | MAPTPOLBNPC1RAB9A | |
| SCHEMBL11799261 | 0.74 | LCLAT1 (0.49) | MAPTPOLBTP53RXFP1RAB9A | |
| SCHEMBL11726576 | 0.73 | CASP3 (0.48) | MAPTPOLBTP53RXFP1NPC1 | |
| SCHEMBL6267898 | 0.72 | MAPT (0.63) | MAPTPOLBTP53NPC1MAPK1 | |
| SCHEMBL27218089 | 0.71 | MAPT (0.55) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065563-A | 3-Hetero-5-isothiocyanophenyl oxadiazoles as antifungal and antibacterial agents | E. R. SQUIBB & SONS, INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4022901-A | FUNGICIDAL AND BACTERICIDAL ACTIVITY | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3976657-A | 3-Hetero-5-substituted aminophenyloxadiazoles | E. R. SQUIBB & SONS, INC. (US) | 1976-08-24 | — | — | US | disclosed |