SCHEMBL11729902

SCHEMBL11729902

CC1(C)OCNc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.38
PDK4 Q16654 1/20 0.38
POLB P06746 3/20 0.37
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 2/20 0.36
KDM1A O60341 1/20 0.36
MAPK1 P28482 1/20 0.36
HTR5A P47898 2/20 0.35
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
ALOX12 P18054 2/20 0.33
HPGD P15428 1/20 0.33
BACE1 P56817 1/20 0.32
ALOX5 P09917 1/20 0.31
CYP1A2 P05177 1/20 0.31
BCHE P06276 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6881522 0.76 ALDH1A1 (0.43) PDK2PDK4POLBALDH1A1MEN1
SCHEMBL6865487 0.76 ALDH1A1 (0.33) PDK2PDK4POLBALDH1A1MEN1
SCHEMBL31306861 0.71 CYP2D6 (0.36) POLBALDH1A1MEN1KMT2AGAA
SCHEMBL24736532 0.71 BACE1 (0.41) POLBALDH1A1MEN1KMT2AGAA
SCHEMBL17203069 0.69 BACE1 (0.44) POLBALDH1A1MEN1KMT2AGAA
SCHEMBL6883483 0.69 POLB (0.36) POLBALDH1A1
SCHEMBL1031209 0.68 PDK2 (0.42) PDK2PDK4POLBKDM1AHTR5A
SCHEMBL29384370 0.68 PDK2 (0.42) PDK2PDK4POLBKDM1AHTR5A
SCHEMBL17202972 0.67 HTR2A (0.43) POLBALDH1A1MEN1KMT2AGAA
SCHEMBL17202816 0.67 BACE1 (0.42) PDK2PDK4POLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4030906-A Herbicidal N-haloacetyl-1,2-dihydro-4H-3,1-benzoxazine CHEVRON RESEARCH COMPANY (US) 1977-06-21 US disclosed