Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731320 | 0.90 | TSHR (0.43) | NPSR1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL11732812 | 0.88 | GAA (0.46) | TSHRKDM4EHPGDP2RX4CCR1 | |
| SCHEMBL11726803 | 0.86 | KDM4E (0.48) | MEN1KMT2ATSHRKDM4EHPGD | |
| SCHEMBL11726925 | 0.84 | TSHR (0.46) | TSHRKDM4ECCR1CHRM2CHRM1 | |
| SCHEMBL11730291 | 0.84 | KDM4E (0.47) | TSHRKDM4EHPGDSMN1; SMN2CCR1 | |
| SCHEMBL11728725 | 0.84 | KDM4E (0.57) | MEN1KMT2ATSHRKDM4EL3MBTL1 | |
| SCHEMBL11731985 | 0.82 | TSHR (0.47) | KMT2ATSHRKDM4EP2RX4CCR1 | |
| SCHEMBL11731515 | 0.82 | TSHR (0.44) | TSHRKDM4EP2RX4CCR1CHRM2 | |
| SCHEMBL11730298 | 0.82 | TSHR (0.43) | NPSR1TSHRKDM4ECCR1LMNA | |
| SCHEMBL11729876 | 0.80 | KDM4E (0.48) | MEN1KMT2ATSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005208-A | GASTRIC JUICE, ANTISECRETORY | SMITHKLINE CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |