Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.39 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728725 | 0.90 | KDM4E (0.57) | TSHRKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL11726925 | 0.88 | TSHR (0.46) | TSHRKDM4EALDH1A1MAPK1CHRM2 | |
| SCHEMBL11731515 | 0.86 | TSHR (0.44) | TSHRKDM4EP2RX4CHRM2CHRM1 | |
| SCHEMBL11730298 | 0.86 | TSHR (0.43) | TSHRKDM4ELMNACHRM2CHRM1 | |
| SCHEMBL11729876 | 0.85 | KDM4E (0.48) | TSHRKDM4EKMT2AALDH1A1LMNA | |
| SCHEMBL11732812 | 0.85 | GAA (0.46) | TSHRKDM4EP2RX4ALDH1A1CHRM2 | |
| SCHEMBL11726803 | 0.85 | KDM4E (0.48) | TSHRKDM4EKMT2AALDH1A1CHRM2 | |
| SCHEMBL11730291 | 0.83 | KDM4E (0.47) | TSHRKDM4EALDH1A1CCR1 | |
| SCHEMBL11730244 | 0.82 | NPSR1 (0.47) | TSHRKDM4EKMT2AP2RX4LMNA | |
| SCHEMBL11731320 | 0.79 | TSHR (0.43) | TSHRKDM4EKMT2AP2RX4CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005208-A | GASTRIC JUICE, ANTISECRETORY | SMITHKLINE CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |