Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399347 | 0.88 | GBA1 (0.54) | GBA1DDB1CRBNGAA | |
| SCHEMBL12040400 | 0.85 | CRBN (0.53) | GBA1DDB1CRBNCCR3GPR84 | |
| SCHEMBL1760901 | 0.85 | GBA1 (0.58) | GBA1DDB1CRBNCCR3GPR84 | |
| SCHEMBL5675291 | 0.78 | GBA1 (0.57) | GBA1DDB1CRBNCCR3GRIN2B | |
| SCHEMBL87612 | 0.76 | GBA1 (1.00) | GBA1CCR3SIGMAR1 | |
| SCHEMBL25698327 | 0.75 | GBA1 (0.50) | GBA1DDB1CRBN | |
| SCHEMBL25698328 | 0.75 | DDB1 (0.46) | GBA1DDB1CRBNCCR3GPR84 | |
| Formaldehyde SCHEMBL28466516 | 0.75 | GBA1 (0.89) | GBA1CCR3 | |
| Hydrochloric Acid SCHEMBL4935892 | 0.74 | GBA1 (0.96) | GBA1CCR3 | |
| Bromide SCHEMBL10728442 | 0.74 | GBA1 (0.96) | GBA1CCR3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003907-A | Δ1 -1-Azacycloalkene-2-carboxylic acids and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | claimed |
| US-4003907-A | Δ1 -1-Azacycloalkene-2-carboxylic acids and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | disclosed |