SCHEMBL87612

SCHEMBL87612

c1ccc(CC2CCNCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 1.00
CCR3 P51677 2/20 0.53
SLC6A4 P31645 1/20 0.51
PRMT3 O60678 1/20 0.49
CARM1 Q86X55 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
PRMT1 Q99873 1/20 0.49
PRMT8 Q9NR22 1/20 0.49
POLB P06746 1/20 0.48
SLC18A3 Q16572 1/20 0.48
SIGMAR1 Q99720 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL10728442 0.98 GBA1 (0.96) GBA1CCR3SLC6A4PRMT3CARM1
Hydrochloric Acid SCHEMBL4935892 0.98 GBA1 (0.96) GBA1CCR3SLC6A4PRMT3CARM1
Formaldehyde SCHEMBL28466516 0.94 GBA1 (0.89) GBA1CCR3SLC6A4PRMT3CARM1
SCHEMBL1428015 0.92 GBA1 (0.85) GBA1CCR3SLC6A4SLC18A3
SCHEMBL8891663 0.92 GBA1 (0.85) GBA1CCR3SLC6A4POLBSLC18A3
SCHEMBL8101593 0.91 GBA1 (0.82) GBA1CCR3SLC6A4PRMT3CARM1
Ethylamine SCHEMBL3323945 0.91 GBA1 (0.82) GBA1CCR3SLC6A4PRMT3CARM1
SCHEMBL28128332 0.91 GBA1 (0.82) GBA1CCR3SLC6A4
SCHEMBL9400535 0.89 GBA1 (0.79) GBA1CCR3
Hydrochloric Acid SCHEMBL28021554 0.89 GBA1 (0.79) GBA1CCR3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3213 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2026-03-10 US claimed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
US-12528777-B2 Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-01-20 US claimed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP claimed
CN-116768826-B Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2025-05-27 CN claimed
CN-120035580-A Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents 基因密码公司 2025-05-23 CN claimed
CN-119977931-A Derivatives having a homoisoflavone-O-alkylamine structure and uses thereof 合肥工业大学 2025-05-13 CN claimed
CN-119948015-A Novel sulfonamides and their use as neuroprotective and/or nerve repair agents 基因密码公司 2025-05-06 CN claimed
EP-4175718-B1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER UNIV CLAUDE BERNARD LYON (FR) 2024-10-02 EP claimed
CN-115843271-B Indole derivatives and their use for the treatment of cancer 克洛德贝纳尔-里昂第一大学 2024-08-13 CN claimed
US-4613596-A ANTAGONISTS FOR HISTAMINE H2 RECEPTORS, ANTIULCER, SKIN DISORDERS MAGIS FARMACEUTRICI S.R.L. (IT) 1986-09-23 US claimed
EP-0188805-A1 1,3-Dithiole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-07-30 EP claimed
EP-0039051-B1 MANNICH-BASE HYDROXAMIC ACID PRODRUGS FOR THE IMPROVED BIOAVAILABILITY OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS, A PROCESS FOR PREPARING AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM MERCK & CO. INC. (US) 1985-07-24 EP claimed
EP-0063084-B1 PHENETHANOL AMINE DERIVATIVES, THEIR PREPARATION AND USE IN MEDICINE SYNTHELABO (FR) 1984-09-12 EP claimed
EP-0092647-A1 New active compounds in the treatment of ulcers and skin allergy symptoms MAGIS FARMACEUTICI S.p.A. (IT) 1983-11-02 EP claimed
US-4412994-A AMINE COMPOUNDS CONTAINING THE ACYL RESIDUE OF INDOMETHACIN AS A SUBSTITUENT INTERX RESEARCH CORPORATION (US) 1983-11-01 US claimed
EP-0051278-A1 Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1982-05-12 EP claimed
EP-0039051-A2 Mannich-base hydroxamic acid prodrugs for the improved bioavailability of non-steroidal anti-inflammatory agents, a process for preparing and a pharmaceutical composition containing them MERCK & CO. INC. (US) 1981-11-04 EP claimed
US-4139626-A FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1979-02-13 US claimed
US-4021400-A SECONDARY AMINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-03 US claimed