Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501810 | 0.81 | ALOX15 (0.35) | ALOX15 | |
| SCHEMBL9168723 | 0.81 | ALOX15 (0.35) | ALOX15MEN1KMT2AGSK3B | |
| SCHEMBL15470460 | 0.81 | ALOX15 (0.35) | ALOX15 | |
| SCHEMBL10500977 | 0.75 | ALOX15 (0.36) | ALOX15NEK6MEN1GAATHRB | |
| SCHEMBL12220350 | 0.74 | ALOX15 (0.39) | ALOX15NEK6MEN1GAATHRB | |
| SCHEMBL12588803 | 0.71 | ALOX15 (0.37) | ALOX15NEK6MEN1GAATHRB | |
| SCHEMBL9770871 | 0.69 | ALOX15 (0.52) | ALOX15MEN1GAATHRBKMT2A | |
| SCHEMBL615573 | 0.67 | MEN1 (0.31) | ALOX15MEN1GAATHRBKMT2A | |
| SCHEMBL9812290 | 0.65 | ALOX15 (0.30) | ALOX15MEN1GAATHRBKMT2A | |
| Methane SCHEMBL1176537 | 0.65 | ALOX15 (0.30) | ALOX15MEN1GAATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | BASF SE (DE) | 2014-02-13 | — | — | US | disclosed |
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | BASF SE (DE) | 2014-02-13 | — | — | US | disclosed |
| US-4057432-A | PHOTOGRAPHIC COUPLERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | CYP51A1, DDT, DPM1 | ALOX15 2054/4885NEK6 2958/4885MEN1 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.