Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 17/20 | 0.64 |
| ▸ | ACHE | P22303 | 8/20 | 0.62 |
| ▸ | CNR1 | P21554 | 6/20 | 0.61 |
| ▸ | CNR2 | P34972 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732317 | 0.95 | APP (0.64) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11732345 | 0.90 | APP (0.84) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11734779 | 0.88 | APP (0.65) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11672066 | 0.88 | BCHE (0.71) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11731490 | 0.87 | APP (0.76) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11729101 | 0.87 | APP (0.63) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11732911 | 0.86 | APP (0.60) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11673919 | 0.82 | APP (0.84) | APPBCHEACHECNR1CNR2 | |
| SCHEMBL11726697 | 0.82 | L3MBTL1 (0.79) | BCHECNR1CNR2 | |
| SCHEMBL11673104 | 0.82 | APP (0.73) | APPBCHEACHECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |