Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.73 |
| ▸ | MEN1 | O00255 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.73 |
| ▸ | TP53 | P04637 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.73 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.73 |
| ▸ | AR | P10275 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavonol SCHEMBL29433939 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| SCHEMBL26661232 | 0.85 | KDM4E (0.65) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL20246 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL1679068 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL31328341 | 0.83 | KDM4E (0.97) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL31570209 | 0.83 | KDM4E (0.97) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL21874433 | 0.83 | KDM4E (0.97) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL21874432 | 0.83 | KDM4E (0.97) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL2386663 | 0.83 | KDM4E (0.97) | KDM4ECYP3A4MEN1KMT2AALOX15 | |
| Flavonol SCHEMBL28055468 | 0.83 | KDM4E (0.97) | KDM4ECYP3A4MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409548-A | A kind of preparation method of 2,2 '-dihydroxy benaophenonel class compounds | 北京吉海川科技发展有限公司 | 2018-08-17 | — | — | CN | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |