Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 12/20 | 0.48 |
| ▸ | RAB9A | P51151 | 10/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418792 | 0.84 | NPC1 (0.60) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11734953 | 0.82 | NPC1 (0.59) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11729485 | 0.79 | LMNA (0.49) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11728204 | 0.79 | LMNA (0.49) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11730127 | 0.78 | LMNA (0.51) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11737313 | 0.77 | NPC1 (0.51) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11732020 | 0.77 | LMNA (0.50) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11730171 | 0.76 | LMNA (0.49) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11734676 | 0.76 | NPC1 (0.68) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11732709 | 0.74 | NPC1 (0.50) | CYP3A4LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009164-A | Novel 2-substituted-1,2,4-thiadiazole-[2,3-a]-benzimidazoles and process for their preparation | SYNTEX (U.S.A.) INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3976654-A | FUNGICIDE | SYNTEX (U.S.A.) INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3946031-A | FUNGICIDES | SYNTEX INC. (US) | 1976-03-23 | — | — | US | disclosed |