Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733347 | 1.00 | NPC1 (0.45) | NPC1RAB9APTPN11PLAUGRIN2D | |
| SCHEMBL7699959 | 0.90 | NPC1 (0.45) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL7699961 | 0.90 | NPC1 (0.45) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL9007267 | 0.88 | NPC1 (0.44) | NPC1RAB9APTPN11PLAUGRIN2D | |
| SCHEMBL9007271 | 0.88 | NPC1 (0.44) | NPC1RAB9APTPN11PLAUGRIN2D | |
| SCHEMBL7523500 | 0.84 | NPC1 (0.41) | NPC1RAB9APTPN11PLAUGRIN2D | |
| SCHEMBL7523501 | 0.84 | NPC1 (0.41) | NPC1RAB9APTPN11PLAUGRIN2D | |
| SCHEMBL9182261 | 0.83 | GAA (0.50) | NPC1RAB9APTPN11PLAUHSD17B10 | |
| SCHEMBL9182266 | 0.83 | GAA (0.50) | NPC1RAB9APTPN11PLAUHSD17B10 | |
| SCHEMBL9007330 | 0.82 | NPC1 (0.40) | NPC1RAB9APTPN11PLAUCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041044-A | BY REDUCTION OF CORRESPONDING O-NITRO-AZOBENZENES WITH ZINC IN AQUEOUS ALKALI METAL HYDROXIDE | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |