Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007314 | 1.00 | NPC1 (0.40) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL5186255 | 0.83 | NPC1 (0.39) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL7699961 | 0.82 | NPC1 (0.45) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL11733352 | 0.82 | NPC1 (0.45) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL7699959 | 0.82 | NPC1 (0.45) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL11733347 | 0.82 | NPC1 (0.45) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL9260980 | 0.81 | PTPN11 (0.40) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL5186248 | 0.81 | PTPN11 (0.40) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL9007271 | 0.81 | NPC1 (0.44) | NPC1RAB9APTPN11CES2ACHE | |
| SCHEMBL9007267 | 0.81 | NPC1 (0.44) | NPC1RAB9APTPN11CES2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571924-A | Process for the preparation of benzotriazoles | CIBA-GEIGY CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| US-5276161-A | Catalytic hydrogenation of o-nitrophenylazohydroxyphenyl compounds; noble metal catalyst and organic amine | CIBA-GEIGY CORPORATION (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0419412-B1 | Process for the preparation of benzotriazoles | CIBA GEIGY AG (CH) | 1993-11-10 | — | — | EP | disclosed |
| EP-0419412-A2 | Process for the preparation of benzotriazoles | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |