Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29312347 | 0.76 | LMNA (0.40) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL13294314 | 0.75 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL13444691 | 0.74 | — | — | |
| SCHEMBL1038259 | 0.74 | — | — | |
| SCHEMBL28377554 | 0.74 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL11725368 | 0.74 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL12676879 | 0.73 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL4324009 | 0.72 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL4324007 | 0.72 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 | |
| SCHEMBL28941090 | 0.72 | MAPT (0.38) | TSHRSMN1; SMN2ALDH1A1TDP1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009128-A | Polymerization of epoxides | HERCULES INCORPORATED (US) | 1977-02-22 | — | — | US | disclosed |