Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.62 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407433 | 0.88 | CXCR1 (0.62) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL4971640 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL11874002 | 0.83 | CXCR1 (0.68) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL915213 | 0.83 | MEN1 (0.64) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL1663739 | 0.82 | MAPT (0.56) | SMN1; SMN2LMNAKMT2AMEN1RAB9A | |
| SCHEMBL4380684 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL7161691 | 0.82 | MAPT (0.74) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL1024223 | 0.81 | CXCR2 (0.68) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL1024222 | 0.81 | CXCR2 (0.68) | SMN1; SMN2LMNAHTTCXCR1CXCR2 | |
| SCHEMBL8407519 | 0.81 | MAPT (0.64) | SMN1; SMN2LMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025642-A | ANTIALLERGENS | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |