Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.62 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131627 | 0.87 | CXCR1 (0.62) | MEN1KMT2ACXCR1CXCR2KCNMA1 | |
| SCHEMBL31171007 | 0.87 | CXCR1 (0.62) | MEN1KMT2ACXCR1CXCR2KCNMA1 | |
| SCHEMBL1024223 | 0.85 | CXCR2 (0.68) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL1024222 | 0.85 | CXCR2 (0.68) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL11874002 | 0.84 | CXCR1 (0.68) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL4326710 | 0.83 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2HTTGAAMAPT | |
| SCHEMBL427418 | 0.83 | HTT (0.67) | MEN1KMT2ACTDSP1SMN1; SMN2LMNA | |
| SCHEMBL11132091 | 0.83 | MEN1 (0.59) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL18600723 | 0.83 | SMN1; SMN2 (0.71) | MEN1KMT2APABPC1DUSP3PTPN5 | |
| SCHEMBL11733765 | 0.83 | SMN1; SMN2 (0.64) | MEN1KMT2APABPC1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4519997-A | COMPLEXES OF TRIVALENT COBALT WITH INORGANIC LIGANDS | VEB-LEUNA-WERKE "WALTER ULBRICHT" (DE) | 1985-05-28 | — | — | US | claimed |
| EP-0029964-A1 | Coupler components for oxidation hair dyes, their production and use, and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-06-10 | — | — | EP | claimed |
| WO-2023031308-A1 | CCR2 INHIBITORS | ARTICA THERAPEUTICS B.V. (NL) | 2023-03-09 | — | — | WO | disclosed |
| US-8853230-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853230-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853230-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130137673-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-20130137673-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-20130137673-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-8367689-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367689-B2 | Inhibitors of JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-4333730-A | HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-08 | — | — | US | disclosed |
| EP-0011844-B1 | COUPLING COMPONENTS FOR OXIDIZING HAIR DYES, THEIR PREPARATION AND HAIR DYES CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-05-26 | — | — | EP | disclosed |
| US-4330292-A | CONTAINING AN OXIDATION BASE | L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |
| US-4314809-A | BIS/2,4-DIAMINOPHENOXY/ALKANES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-02-09 | — | — | US | disclosed |
| EP-0029964-A1 | Coupler components for oxidation hair dyes, their production and use, and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-06-10 | — | — | EP | disclosed |
| US-4231964-A | Nitroamines, processes for their manufacture and their use as diazo components | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-04 | — | — | US | disclosed |
| EP-0011844-A1 | Coupling components for oxidizing hair dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |
| US-4102879-A | COLORFASTNESS | BASF AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
| US-4025642-A | ANTIALLERGENS | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137673-A1 | INHIBITORS OF JAK | JAK1, JAK2, JAK3 | MEN1 2502/4885KMT2A 1528/4885PABPC1 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.