Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726950 | 0.88 | NR1I2 (0.54) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11730879 | 0.88 | NR1I2 (0.70) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11723933 | 0.83 | NR1I2 (0.77) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11725275 | 0.82 | NR1I2 (0.55) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11725572 | 0.79 | CASR (0.56) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11724593 | 0.76 | NR1I2 (0.70) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11565990 | 0.75 | NR1I2 (0.85) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11601877 | 0.72 | CASR (0.67) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Fluproquazone SCHEMBL29363976 | 0.71 | NR1I2 (0.77) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| Fluproquazone SCHEMBL26210 | 0.71 | NR1I2 (0.77) | NR1I2EGFRADRA2AADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064246-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1977-12-20 | — | — | US | disclosed |