Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734526 | 0.84 | GPR84 (0.51) | EPHX1FAAHGPR84L3MBTL1CETP | |
| SCHEMBL5678305 | 0.84 | SRC (0.40) | FAAHHPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11658493 | 0.82 | SRC (0.52) | L3MBTL1RAB9AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL4131480 | 0.79 | KMT2A (0.49) | HPGDRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7878424 | 0.78 | GPR84 (0.63) | GPR84L3MBTL1CETPHPGDRAB9A | |
| SCHEMBL4137886 | 0.77 | GPR84 (0.41) | GPR84L3MBTL1HPGDHTTMAPT | |
| SCHEMBL18632041 | 0.76 | NPC1 (0.41) | EPHX1HPGDRAB9AKMT2ALMNA | |
| SCHEMBL2344043 | 0.75 | GPR84 (0.63) | GPR84CETPRAB9AHTTMAPT | |
| SCHEMBL29848582 | 0.75 | GPR84 (0.63) | GPR84CETPRAB9AHTTMAPT | |
| SCHEMBL10792972 | 0.74 | GPR84 (0.58) | GPR84L3MBTL1CETPHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041111-A | PHOSPHONIC ACID DICHLORIDE REACTED WITH 2-NAPHTHOL OR 4-NITRO-PHENOL, HYDROLYSIS | PURDUE RESEARCH FOUNDATION (US) | 1977-08-09 | — | — | US | claimed |