Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803468 | 0.86 | CES2 (0.36) | CES2CES1 | |
| SCHEMBL29132605 | 0.79 | CES1 (0.44) | CES2CES1 | |
| SCHEMBL3056362 | 0.76 | CYP1A2 (0.35) | GAA | |
| SCHEMBL28697618 | 0.76 | CES1 (0.46) | CES2CES1 | |
| SCHEMBL2580699 | 0.74 | CES1 (0.41) | CES2CES1 | |
| SCHEMBL4870644 | 0.74 | CES1 (0.34) | CES2CES1 | |
| SCHEMBL11995881 | 0.74 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL7558796 | 0.73 | CES1 (0.47) | CES2CES1 | |
| SCHEMBL2580479 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL7558673 | 0.73 | CES1 (0.47) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758567-A4 | PARTIALLY-FLUORINATED ETHERS, COMPOSITIONS AND USES THEREOF, FOR LONG-TERM TAMPONADE IN THE EYE | UNIV COLUMBIA (US) | 2008-03-12 | — | — | EP | claimed |
| US-20070219162-A1 | Partially-fluorinated ethers, compositions and uses thereof, for long-term tamponade in the eye | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-09-20 | — | — | US | claimed |
| EP-1758567-A1 | PARTIALLY-FLUORINATED ETHERS, COMPOSITIONS AND USES THEREOF, FOR LONG-TERM TAMPONADE IN THE EYE | The Trustees of Columbia University in the City of New York (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2005117850-A1 | PARTIALLY-FLUORINATED ETHERS, COMPOSITIONS AND USES THEREOF, FOR LONG-TERM TAMPONADE IN THE EYE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) | 2005-12-15 | — | — | WO | claimed |
| EP-2294044-B1 | FLUOROALKYLOXY ALKANES, PROCESS FOR PRODUCTION AND USES THEREOF | AL CHI MI A S R L (IT) | 2016-07-13 | — | — | EP | disclosed |
| EP-2294044-A1 | FLUOROALKYLOXY ALKANES, PROCESS FOR PRODUCTION AND USES THEREOF | AL.CHI.MI.A. S.r.l. (IT) | 2011-03-16 | — | — | EP | disclosed |
| US-20110034414-A1 | FLUOROALKYLOXY ALKANES, PROCESS FOR PRODUCTION AND USES THEREOF | AL.CHI.MI.A. S.R.L. (IT) | 2011-02-10 | — | — | US | disclosed |
| WO-2009133575-A1 | FLUOROALKYLOXY ALKANES, PROCESS FOR PRODUCTION AND USES THEREOF | AL.CHI.MI.A. S.R.L. (IT) | 2009-11-05 | — | — | WO | disclosed |
| EP-1758567-A4 | PARTIALLY-FLUORINATED ETHERS, COMPOSITIONS AND USES THEREOF, FOR LONG-TERM TAMPONADE IN THE EYE | UNIV COLUMBIA (US) | 2008-03-12 | — | — | EP | disclosed |
| US-20070219162-A1 | Partially-fluorinated ethers, compositions and uses thereof, for long-term tamponade in the eye | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-09-20 | — | — | US | disclosed |
| EP-1758567-A1 | PARTIALLY-FLUORINATED ETHERS, COMPOSITIONS AND USES THEREOF, FOR LONG-TERM TAMPONADE IN THE EYE | The Trustees of Columbia University in the City of New York (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005117850-A1 | PARTIALLY-FLUORINATED ETHERS, COMPOSITIONS AND USES THEREOF, FOR LONG-TERM TAMPONADE IN THE EYE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) | 2005-12-15 | — | — | WO | disclosed |