Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741875 | 0.91 | MAPT (0.42) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11735989 | 0.88 | SMN1; SMN2 (0.37) | MAPTTHRBKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL11740365 | 0.87 | MAPT (0.42) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11738569 | 0.87 | MAPT (0.40) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11735715 | 0.85 | MAPT (0.40) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11735667 | 0.84 | SMN1; SMN2 (0.43) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11737536 | 0.84 | MAPT (0.38) | MAPTKDM4ESMN1; SMN2HSD17B10TP53 | |
| SCHEMBL11729614 | 0.83 | KDM4E (0.48) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11736358 | 0.83 | KDM4E (0.41) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL11739244 | 0.83 | MAPT (0.40) | MAPTKDM4ESMN1; SMN2HSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041163-A | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents | PFIZER INC. (US) | 1977-08-09 | — | — | US | disclosed |